BIRI Study for Development & Validation of Novel MR-PET Imaging Techniques

Condition: Coronary artery disease, peripheral vascular disease, cancers


Key Inclusion Criteria

  • At least 18 years old with body mass index less than 30
  • Diagnosed with or undergoing evaluation for cardiovascular, nervous system diseases or solid-organ cancers

Key Exclusion Criteria

  • Individuals with mechanically, magnetically or electrically activated implants; those with ferromagnetic implants and ferromagnetic foreign bodies
  • Pregnant, nursing or implanted with intrauterine devices (IUD’s) that are not MR compatible

Full Study Name

Biomedical Imaging Research Institute (BIRI) Study for Development and Validation of Novel MR-PET Imaging Techniques (IRB no. 39909)


Using the hybrid Siemens Biograph mMr (PET-MR) scanner, researchers simultaneously acquire MR and PET data across the whole body. Biomedical Imaging Research Institute scientists focus on developing new imaging techniques to answer a wide array of research and clinical questions, where producing a single scan that reveals both functional and anatomical information would create a more complete diagnostic tool. In collaboration with medical specialists, pulse sequences (software) are validated in patients undergoing evaluation for numerous diseases, including many types of heart disease, peripheral and intracranial (brain) neurological diseases, cancers, spine problems, urology and other nervous system disorders. The long-term goal of this study is to develop new techniques that would translate to clinical significance.

Principal Investigator

Debiao Li, MD