Pulmonary Hypertension Clinical Trials

As a patient at Cedars-Sinai, you will have access to the latest clinical trials and research for pulmonary hypertension. Backed by a respected team of specialists and researchers, our clinical trials aim to further the advancement of diagnosing and treating your condition.

Questions? See the Clinical Trials FAQs.


Idiopathic, heritable, connective tissue disease-associated and HIV-associated pulmonary arterial hypertension

Key Inclusion Criteria:

  • Confirmed clinical diagnosis of IPAH, HPAH, PAH-CTD, PAH-HIV
  • NYHA Functional Class: II or III
  • 18-75 years old


This study focuses on patients with pulmonary arterial hypertension (PAH) from the following subgroups: idiopathic PAH (IPAH), heritable PAH (HPAH), PAH associated with connective tissue disease (PAH-CTD) and PAH associated with HIV (PAH-HIV). The study is designed to evaluate the investigational use of a biologic product called CAP-1002. CAP-1002 consists largely of heart stem cells ("CDCs") grown from donated tissue from human heart muscle. The purpose of the study is to determine the maximum feasible dose and safety of CAP-1002 administered by central intravenous infusion (IV line) in PAH patients belonging to one of the subgroups listed above who have been started on PAH-specific medications. CAP-1002 will be used in addition to the participant’s regular treatment regimen.

Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYST


Connective Tissue Disease-Associated Pulmonary Arterial Hypertension

CAPERE Thrombectomy System Post-Market Clinical Follow Up Study


Observational Study

Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization


Critical Limb Ischemia (CLI)

Evaluating the Safety and Efficacy of the Indigo® Aspiration System in Acute Pulmonary Embolism (EXTRACT-PE)


Pulmonary Embolism

Extended Access Program to Assess Long-term Safety of Bardoxolone Methyl in Patients With Pulmonary Hypertension RANGER (RANGER)


Pulmonary Hypertension

An International Pulmonary Embolism Registry Using EKOS (KNOCOUT PE)


Pulmonary Embolism and Thrombosis

An Open Label Extension Study to Evaluate Inhaled Treprostinil in Adult PH With ILD Including CPFE


Pulmonary Hypertension, Interstitial Lung Disease, Combined Pulmonary Fibrosis and Emphysema

Oral Treprostinil in Subjects With Pulmonary Hypertension Associated With Heart Failure With Preserved Ejection Fraction


Pulmonary Hypertension, Heart Failure With a Preserved Ejection Fraction

Shockwave Medical Peripheral Lithoplasty System Study for PAD (Disrupt PAD III)


Peripheral Arterial Disease

A Study to Evaluate Whether Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease (SERENADE)


Heart Failure With Preserved Ejection Fraction

Study of Oral Treprostinil in Subjects With Pulmonary Hypertension (PH) Associated With Heart Failure With Preserved Ejection Fraction (HFpEF)


Pulmonary Hypertension Associated With HFpEF

TRACER [F-18] RDG-K5 Carotid Plaque Imaging Study (K5-C200)


Carotid Arteries