Valvular Heart Disease Clinical Trials
As a patient at Cedars-Sinai, you will have access to the latest clinical trials and research for valvular heart disease. Backed by a respected team of specialists and researchers, our clinical trials aim to further the advancement of diagnosing and treating your condition.
Questions? See the Clinical Trials FAQs.
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) (COAPT)
Mitral Regurgitation, Mitral Valve Regurgitation, Treatment of Functional Mitral Regurgitation in Symptomatic Heart Failure Subjects, Heart Failure
Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (SUMMIT)
Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Insufficiency, Cardiovascular Diseases, Valve Disease (Heart), Heart Valve Diseases, Functional Mitral Regurgitation, Degenerative Mitral Valve Disease
Mitral valve regurgitation
- Adult patients ≥65 years old with moderately severe or severe primary
degenerative mitral valve regurgitation (MR)
- Clinical indication for mitral valve (MV) intervention and anatomic candidate for both MV transcatheter edge-to-edge and surgical repair
- Patients across the surgical risk spectrum (low, intermediate, and high risk)
The purpose of this study is to compare the risks and benefits of two procedures used to help patients with mitral valve regurgitation (MR). The study will compare transcatheter edge-to-edge repair (TEER- a catheter procedure for repairing the mitral valve that does not require surgery to open up the heart) and mitral valve repair surgery, an open-heart surgical procedure.