We are studying immune responses in the lung, gut and at other mucosal surfaces, and investigating how commensal microbes in these locations interact with the immune system to maintain health or cause disease.
Janine Bilsborough – functional defects in microbial recognition at the gut-microbe interface in Inflammatory Bowel Disease (IBD)
Jonathan Braun – metabolites of the intestinal microbiome; role of the intestinal microbiome in epithelial development and carcinogenesis
Peter Chen – microbiome effects on lung immunity during influenza infection
We are studying the role of immune cells and inflammation in the brain and other parts of the nervous system with the goal of developing immune-targeting strategies to prevent and treat neurodegenerative diseases.